diff --git a/Marlin/Conditionals_LCD.h b/Marlin/Conditionals_LCD.h
index 3f9da4adb..2cd750432 100644
--- a/Marlin/Conditionals_LCD.h
+++ b/Marlin/Conditionals_LCD.h
@@ -380,12 +380,6 @@
 
 #define HAS_DEBUG_MENU (ENABLED(ULTIPANEL) && ENABLED(LCD_PROGRESS_BAR_TEST))
 
-// MK2 Multiplexer forces SINGLENOZZLE and kills DISABLE_INACTIVE_EXTRUDER
-#if ENABLED(MK2_MULTIPLEXER)
-  #define SINGLENOZZLE
-  #undef DISABLE_INACTIVE_EXTRUDER
-#endif
-
 /**
  * Extruders have some combination of stepper motors and hotends
  * so we separate these concepts into the defines:
@@ -416,6 +410,16 @@
   #define E_MANUAL        EXTRUDERS
 #endif
 
+// No inactive extruders with MK2_MULTIPLEXER or SWITCHING_NOZZLE
+#if ENABLED(MK2_MULTIPLEXER) || ENABLED(SWITCHING_NOZZLE)
+  #undef DISABLE_INACTIVE_EXTRUDER
+#endif
+
+// MK2 Multiplexer forces SINGLENOZZLE
+#if ENABLED(MK2_MULTIPLEXER)
+  #define SINGLENOZZLE
+#endif
+
 #if ENABLED(SINGLENOZZLE) || ENABLED(MIXING_EXTRUDER)         // One hotend, one thermistor, no XY offset
   #undef HOTENDS
   #define HOTENDS       1