diff --git a/Marlin/Marlin_main.cpp b/Marlin/Marlin_main.cpp
index 1f44fdca7..7ef28de08 100644
--- a/Marlin/Marlin_main.cpp
+++ b/Marlin/Marlin_main.cpp
@@ -13236,7 +13236,10 @@ void disable_all_steppers() {
 void manage_inactivity(bool ignore_stepper_queue/*=false*/) {
 
   #if ENABLED(FILAMENT_RUNOUT_SENSOR)
-    if ((IS_SD_PRINTING || print_job_timer.isRunning()) && (READ(FIL_RUNOUT_PIN) == FIL_RUNOUT_INVERTING))
+    if ((IS_SD_PRINTING || print_job_timer.isRunning())
+       && READ(FIL_RUNOUT_PIN) == FIL_RUNOUT_INVERTING
+       && thermalManager.targetHotEnoughToExtrude(active_extruder)
+    )
       handle_filament_runout();
   #endif