diff --git a/Marlin/src/HAL/STM32/HAL.cpp b/Marlin/src/HAL/STM32/HAL.cpp
index 83604b1104..c886f9c0b9 100644
--- a/Marlin/src/HAL/STM32/HAL.cpp
+++ b/Marlin/src/HAL/STM32/HAL.cpp
@@ -81,7 +81,9 @@ void HAL_init() {
 
   SetTimerInterruptPriorities();
 
-  TERN_(EMERGENCY_PARSER, USB_Hook_init());
+  #if ENABLED(EMERGENCY_PARSER) && USBD_USE_CDC
+    USB_Hook_init();
+  #endif
 }
 
 void HAL_clear_reset_source() { __HAL_RCC_CLEAR_RESET_FLAGS(); }
@@ -128,8 +130,12 @@ uint16_t HAL_adc_get_result() { return HAL_adc_result; }
 void flashFirmware(const int16_t) { NVIC_SystemReset(); }
 
 // Maple Compatibility
+volatile uint32_t systick_uptime_millis = 0;
 systickCallback_t systick_user_callback;
 void systick_attach_callback(systickCallback_t cb) { systick_user_callback = cb; }
-void HAL_SYSTICK_Callback() { if (systick_user_callback) systick_user_callback(); }
+void HAL_SYSTICK_Callback() {
+  systick_uptime_millis++;
+  if (systick_user_callback) systick_user_callback();
+}
 
 #endif // ARDUINO_ARCH_STM32 && !STM32GENERIC
diff --git a/Marlin/src/HAL/STM32/HAL.h b/Marlin/src/HAL/STM32/HAL.h
index a1f7515d6b..3cd138ba61 100644
--- a/Marlin/src/HAL/STM32/HAL.h
+++ b/Marlin/src/HAL/STM32/HAL.h
@@ -184,3 +184,4 @@ void flashFirmware(const int16_t);
 typedef void (*systickCallback_t)(void);
 void systick_attach_callback(systickCallback_t cb);
 void HAL_SYSTICK_Callback();
+extern volatile uint32_t systick_uptime_millis;
diff --git a/Marlin/src/HAL/STM32/usb_serial.cpp b/Marlin/src/HAL/STM32/usb_serial.cpp
index 2dd1bef12c..25c47d694f 100644
--- a/Marlin/src/HAL/STM32/usb_serial.cpp
+++ b/Marlin/src/HAL/STM32/usb_serial.cpp
@@ -21,7 +21,7 @@
 
 #include "../../inc/MarlinConfigPre.h"
 
-#if ENABLED(EMERGENCY_PARSER)
+#if ENABLED(EMERGENCY_PARSER) && USBD_USE_CDC
 
 #include "usb_serial.h"
 #include "../../feature/e_parser.h"