diff --git a/Marlin/src/Marlin.cpp b/Marlin/src/Marlin.cpp
index 12bac48b6c..d94fa51ac4 100644
--- a/Marlin/src/Marlin.cpp
+++ b/Marlin/src/Marlin.cpp
@@ -860,7 +860,7 @@ void setup() {
 
   setup_killpin();
 
-  #if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+  #if HAS_TMC220x
     tmc_serial_begin();
   #endif
 
diff --git a/Marlin/src/core/drivers.h b/Marlin/src/core/drivers.h
index a6e480c141..6e89ae8532 100644
--- a/Marlin/src/core/drivers.h
+++ b/Marlin/src/core/drivers.h
@@ -84,6 +84,8 @@
                        || HAS_DRIVER(TMC5130) \
                        || HAS_DRIVER(TMC5160) )
 
+#define HAS_TMC220x (HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209))
+
 #define AXIS_IS_TMC(A)   (    AXIS_DRIVER_TYPE(A,TMC2130) \
                            || AXIS_DRIVER_TYPE(A,TMC2160) \
                            || AXIS_DRIVER_TYPE(A,TMC2208) \
diff --git a/Marlin/src/feature/tmc_util.cpp b/Marlin/src/feature/tmc_util.cpp
index c432a3cf9a..a9c55e8c10 100644
--- a/Marlin/src/feature/tmc_util.cpp
+++ b/Marlin/src/feature/tmc_util.cpp
@@ -69,7 +69,7 @@
          #endif
       ;
     #if ENABLED(TMC_DEBUG)
-      #if HAS_TMCX1X0 || HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+      #if HAS_TMCX1X0 || HAS_TMC220x
         uint8_t cs_actual;
       #endif
       #if HAS_STALLGUARD
@@ -139,7 +139,7 @@
 
   #endif // HAS_TMCX1X0
 
-  #if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+  #if HAS_TMC220x
 
     #if ENABLED(TMC_DEBUG)
       static uint32_t get_pwm_scale(TMC2208Stepper &st) { return st.pwm_scale_sum(); }
@@ -239,7 +239,7 @@
     st.printLabel();
     SERIAL_CHAR(':'); SERIAL_PRINT(pwm_scale, DEC);
     #if ENABLED(TMC_DEBUG)
-      #if HAS_TMCX1X0 || HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+      #if HAS_TMCX1X0 || HAS_TMC220x
         SERIAL_CHAR('/'); SERIAL_PRINT(data.cs_actual, DEC);
       #endif
       #if HAS_STALLGUARD
@@ -516,7 +516,7 @@
     }
   #endif
 
-  #if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+  #if HAS_TMC220x
     static void _tmc_status(TMC2208Stepper &st, const TMC_debug_enum i) {
       switch (i) {
         case TMC_PWM_SCALE: SERIAL_PRINT(st.pwm_scale_sum(), DEC); break;
@@ -789,7 +789,7 @@
     #endif
     TMC_REPORT("CS actual\t",        TMC_CS_ACTUAL);
     TMC_REPORT("PWM scale",          TMC_PWM_SCALE);
-    #if HAS_DRIVER(TMC2130) || HAS_DRIVER(TMC2224) || HAS_DRIVER(TMC2660) || HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+    #if HAS_DRIVER(TMC2130) || HAS_DRIVER(TMC2224) || HAS_DRIVER(TMC2660) || HAS_TMC220x
       TMC_REPORT("vsense\t",         TMC_VSENSE);
     #endif
     TMC_REPORT("stealthChop",        TMC_STEALTHCHOP);
@@ -821,7 +821,7 @@
     DRV_REPORT("s2ga\t",             TMC_S2GA);
     DRV_REPORT("otpw\t",             TMC_DRV_OTPW);
     DRV_REPORT("ot\t",               TMC_OT);
-    #if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+    #if HAS_TMC220x
       DRV_REPORT("157C\t",           TMC_T157);
       DRV_REPORT("150C\t",           TMC_T150);
       DRV_REPORT("143C\t",           TMC_T143);
@@ -845,7 +845,7 @@
       }
     }
   #endif
-  #if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+  #if HAS_TMC220x
     static void tmc_get_ic_registers(TMC2208Stepper, const TMC_get_registers_enum) { SERIAL_CHAR('\t'); }
   #endif
 
diff --git a/Marlin/src/inc/Conditionals_post.h b/Marlin/src/inc/Conditionals_post.h
index 8d6da94e8e..9619003184 100644
--- a/Marlin/src/inc/Conditionals_post.h
+++ b/Marlin/src/inc/Conditionals_post.h
@@ -909,7 +909,7 @@
   #define HAS_TMCX1X0       (HAS_DRIVER(TMC2130) || HAS_DRIVER(TMC2160) || HAS_DRIVER(TMC5130) || HAS_DRIVER(TMC5160))
   #define TMC_HAS_SPI       (HAS_TMCX1X0 || HAS_DRIVER(TMC2660))
   #define HAS_STALLGUARD    (HAS_TMCX1X0 || HAS_DRIVER(TMC2209) || HAS_DRIVER(TMC2660))
-  #define HAS_STEALTHCHOP   (HAS_TMCX1X0 || HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209))
+  #define HAS_STEALTHCHOP   (HAS_TMCX1X0 || HAS_TMC220x)
 
   #define STEALTHCHOP_ENABLED ANY(STEALTHCHOP_XY, STEALTHCHOP_Z, STEALTHCHOP_E)
   #define USE_SENSORLESS EITHER(SENSORLESS_HOMING, SENSORLESS_PROBING)
diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index 0296b72c4e..e6cd29715d 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -2015,7 +2015,7 @@ static_assert(Y_MAX_LENGTH >= Y_BED_SIZE, "Movement bounds (Y_MIN_POS, Y_MAX_POS
 /**
  * TMC2208/2209 software UART and ENDSTOP_INTERRUPTS both use pin change interrupts (PCI)
  */
-#if (HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)) && ENABLED(ENDSTOP_INTERRUPTS_FEATURE) && !( \
+#if HAS_TMC220x && ENABLED(ENDSTOP_INTERRUPTS_FEATURE) && !( \
        defined(X_HARDWARE_SERIAL ) \
     || defined(X2_HARDWARE_SERIAL) \
     || defined(Y_HARDWARE_SERIAL ) \
@@ -2035,7 +2035,7 @@ static_assert(Y_MAX_LENGTH >= Y_BED_SIZE, "Movement bounds (Y_MIN_POS, Y_MAX_POS
 /**
  * TMC2208/2209 software UART is only supported on AVR, LPC, STM32F1 and STM32F4
  */
-#if (HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)) && !defined(__AVR__) && !defined(TARGET_LPC1768) && !defined(TARGET_STM32F1) && !defined(TARGET_STM32F4) && !( \
+#if HAS_TMC220x && !defined(__AVR__) && !defined(TARGET_LPC1768) && !defined(TARGET_STM32F1) && !defined(TARGET_STM32F4) && !( \
        defined(X_HARDWARE_SERIAL ) \
     || defined(X2_HARDWARE_SERIAL) \
     || defined(Y_HARDWARE_SERIAL ) \
diff --git a/Marlin/src/module/stepper_indirection.cpp b/Marlin/src/module/stepper_indirection.cpp
index 362ed01ba9..a97402b948 100644
--- a/Marlin/src/module/stepper_indirection.cpp
+++ b/Marlin/src/module/stepper_indirection.cpp
@@ -309,7 +309,7 @@
 //
 // TMC2208/2209 Driver objects and inits
 //
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   #if AXIS_HAS_UART(X)
     #ifdef X_HARDWARE_SERIAL
       TMC_UART_DEFINE(HW, X, X);
diff --git a/Marlin/src/module/stepper_indirection.h b/Marlin/src/module/stepper_indirection.h
index 0e9c188adc..47fe8b09a1 100644
--- a/Marlin/src/module/stepper_indirection.h
+++ b/Marlin/src/module/stepper_indirection.h
@@ -69,7 +69,7 @@
 
   static constexpr chopper_timing_t chopper_timing = CHOPPER_TIMING;
 
-  #if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+  #if HAS_TMC220x
     void tmc_serial_begin();
   #endif
 #endif
diff --git a/Marlin/src/pins/pins_BIGTREE_SKR_PRO_V1.1.h b/Marlin/src/pins/pins_BIGTREE_SKR_PRO_V1.1.h
index 3b7a89fc84..954c83d922 100644
--- a/Marlin/src/pins/pins_BIGTREE_SKR_PRO_V1.1.h
+++ b/Marlin/src/pins/pins_BIGTREE_SKR_PRO_V1.1.h
@@ -109,7 +109,7 @@
   #define TMC_SW_SCK       PC10
 #endif
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   /**
    * TMC2208 stepper drivers
    *
diff --git a/Marlin/src/pins/pins_BIGTREE_SKR_V1.3.h b/Marlin/src/pins/pins_BIGTREE_SKR_V1.3.h
index 87617fbd83..0db91a83e4 100644
--- a/Marlin/src/pins/pins_BIGTREE_SKR_V1.3.h
+++ b/Marlin/src/pins/pins_BIGTREE_SKR_V1.3.h
@@ -114,7 +114,7 @@
   #endif
 #endif
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
     /**
    * TMC2208/TMC2209 stepper drivers
    *
diff --git a/Marlin/src/pins/pins_FYSETC_F6_13.h b/Marlin/src/pins/pins_FYSETC_F6_13.h
index e41cca85cd..be5ff2a305 100644
--- a/Marlin/src/pins/pins_FYSETC_F6_13.h
+++ b/Marlin/src/pins/pins_FYSETC_F6_13.h
@@ -117,7 +117,7 @@
 // the jumper next to the limit switch socket when using sensorless homing.
 //
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   // Software serial
   // At the moment, F6 rx pins are not pc interrupt pins
   #define X_SERIAL_RX_PIN  -1   // 71
diff --git a/Marlin/src/pins/pins_MKS_SBASE.h b/Marlin/src/pins/pins_MKS_SBASE.h
index 2d37f7274e..8bdece7029 100644
--- a/Marlin/src/pins/pins_MKS_SBASE.h
+++ b/Marlin/src/pins/pins_MKS_SBASE.h
@@ -303,7 +303,7 @@
  #endif
 #endif
 
-#if MB(MKS_SBASE) && (HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209))
+#if MB(MKS_SBASE) && HAS_TMC220x
   // The shortage of pins becomes apparent.
   // Worst case you may have to give up the LCD
   // RX pins need to be interrupt capable
diff --git a/Marlin/src/pins/pins_MKS_SGEN.h b/Marlin/src/pins/pins_MKS_SGEN.h
index 921ec60c36..330fee2dc3 100644
--- a/Marlin/src/pins/pins_MKS_SGEN.h
+++ b/Marlin/src/pins/pins_MKS_SGEN.h
@@ -43,7 +43,7 @@
 //#define BTN_EN1        P1_23   // EXP2.5
 //#define BTN_EN2        P1_22   // EXP2.3
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   // The shortage of pins becomes apparent.
   // In the worst case you may have to give up the LCD.
   // RX pins must be interrupt-capable.
diff --git a/Marlin/src/pins/pins_MKS_SGEN_L.h b/Marlin/src/pins/pins_MKS_SGEN_L.h
index 9d20eb3be9..c43ed141a6 100644
--- a/Marlin/src/pins/pins_MKS_SGEN_L.h
+++ b/Marlin/src/pins/pins_MKS_SGEN_L.h
@@ -108,7 +108,7 @@
   #endif
 #endif
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   /**
    * TMC2208 stepper drivers
    *
diff --git a/Marlin/src/pins/pins_RAMPS.h b/Marlin/src/pins/pins_RAMPS.h
index e79247fcef..8d28f11ff7 100644
--- a/Marlin/src/pins/pins_RAMPS.h
+++ b/Marlin/src/pins/pins_RAMPS.h
@@ -296,7 +296,7 @@
   #endif
 #endif
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   /**
    * TMC2208/TMC2209 stepper drivers
    *
diff --git a/Marlin/src/pins/pins_RAMPS_FD_V1.h b/Marlin/src/pins/pins_RAMPS_FD_V1.h
index 684489403a..a141adab58 100644
--- a/Marlin/src/pins/pins_RAMPS_FD_V1.h
+++ b/Marlin/src/pins/pins_RAMPS_FD_V1.h
@@ -205,7 +205,7 @@
 
 #endif // HAS_SPI_LCD
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   /**
    * TMC2208/TMC2209 stepper drivers
    *
diff --git a/Marlin/src/pins/pins_RAMPS_LINUX.h b/Marlin/src/pins/pins_RAMPS_LINUX.h
index 0176ead97e..104f717d1e 100644
--- a/Marlin/src/pins/pins_RAMPS_LINUX.h
+++ b/Marlin/src/pins/pins_RAMPS_LINUX.h
@@ -269,7 +269,7 @@
   #endif
 #endif
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   /**
    * TMC2208/TMC2209 stepper drivers
    *
diff --git a/Marlin/src/pins/pins_RAMPS_RE_ARM.h b/Marlin/src/pins/pins_RAMPS_RE_ARM.h
index 5ee4e1ad6f..12d20b2943 100644
--- a/Marlin/src/pins/pins_RAMPS_RE_ARM.h
+++ b/Marlin/src/pins/pins_RAMPS_RE_ARM.h
@@ -113,7 +113,7 @@
   #endif
 #endif
 
-#if HAS_DRIVER(TMC2208) || HAS_DRIVER(TMC2209)
+#if HAS_TMC220x
   /**
    * TMC2208/TMC2209 stepper drivers
    *