diff --git a/Marlin/Configuration_adv.h b/Marlin/Configuration_adv.h
index c8e30fffec..088554ebb8 100644
--- a/Marlin/Configuration_adv.h
+++ b/Marlin/Configuration_adv.h
@@ -807,6 +807,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/Marlin_main.cpp b/Marlin/Marlin_main.cpp
index 69296edda2..dd6ec521f7 100644
--- a/Marlin/Marlin_main.cpp
+++ b/Marlin/Marlin_main.cpp
@@ -9265,10 +9265,10 @@ inline void gcode_M503() {
    */
   inline void gcode_M600() {
 
-    // Don't allow filament change without homing first
-    if (axis_unhomed_error()) {
-        home_all_axes();
-    }
+    #if ENABLED(HOME_BEFORE_FILAMENT_CHANGE)
+      // Don't allow filament change without homing first
+      if (axis_unhomed_error()) home_all_axes();
+    #endif
 
     // Initial retract before move to filament change position
     const float retract = parser.seen('E') ? parser.value_axis_units(E_AXIS) : 0
diff --git a/Marlin/SanityCheck.h b/Marlin/SanityCheck.h
index de4f550d2b..ee25709af3 100644
--- a/Marlin/SanityCheck.h
+++ b/Marlin/SanityCheck.h
@@ -321,6 +321,8 @@
     #error "EXTRUDER_RUNOUT_PREVENT is incompatible with ADVANCED_PAUSE_FEATURE."
   #elif ENABLED(PARK_HEAD_ON_PAUSE) && DISABLED(SDSUPPORT) && DISABLED(NEWPANEL) && DISABLED(EMERGENCY_PARSER)
     #error "PARK_HEAD_ON_PAUSE requires SDSUPPORT, EMERGENCY_PARSER, or an LCD controller."
+  #elif ENABLED(HOME_BEFORE_FILAMENT_CHANGE) && DISABLED(PAUSE_PARK_NO_STEPPER_TIMEOUT)
+    #error "HOME_BEFORE_FILAMENT_CHANGE requires PAUSE_PARK_NO_STEPPER_TIMEOUT"
   #endif
 #endif
 
diff --git a/Marlin/example_configurations/Cartesio/Configuration_adv.h b/Marlin/example_configurations/Cartesio/Configuration_adv.h
index 8dfb65a36d..81cf8e290a 100644
--- a/Marlin/example_configurations/Cartesio/Configuration_adv.h
+++ b/Marlin/example_configurations/Cartesio/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/Felix/Configuration_adv.h b/Marlin/example_configurations/Felix/Configuration_adv.h
index a5940d4566..ac5bdb51ce 100644
--- a/Marlin/example_configurations/Felix/Configuration_adv.h
+++ b/Marlin/example_configurations/Felix/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/FolgerTech-i3-2020/Configuration_adv.h b/Marlin/example_configurations/FolgerTech-i3-2020/Configuration_adv.h
index 4174cba825..282fdf006f 100644
--- a/Marlin/example_configurations/FolgerTech-i3-2020/Configuration_adv.h
+++ b/Marlin/example_configurations/FolgerTech-i3-2020/Configuration_adv.h
@@ -809,6 +809,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   #define PARK_HEAD_ON_PAUSE                  // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/Hephestos/Configuration_adv.h b/Marlin/example_configurations/Hephestos/Configuration_adv.h
index 3e7f6416d1..e2ed21f47d 100644
--- a/Marlin/example_configurations/Hephestos/Configuration_adv.h
+++ b/Marlin/example_configurations/Hephestos/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/Hephestos_2/Configuration_adv.h b/Marlin/example_configurations/Hephestos_2/Configuration_adv.h
index 26af260c3e..c70eb7c28a 100644
--- a/Marlin/example_configurations/Hephestos_2/Configuration_adv.h
+++ b/Marlin/example_configurations/Hephestos_2/Configuration_adv.h
@@ -783,6 +783,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/K8200/Configuration_adv.h b/Marlin/example_configurations/K8200/Configuration_adv.h
index 4cad884b71..82d8adbadf 100644
--- a/Marlin/example_configurations/K8200/Configuration_adv.h
+++ b/Marlin/example_configurations/K8200/Configuration_adv.h
@@ -813,6 +813,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/K8400/Configuration_adv.h b/Marlin/example_configurations/K8400/Configuration_adv.h
index 34ccc3aeb3..a49c7d51bd 100644
--- a/Marlin/example_configurations/K8400/Configuration_adv.h
+++ b/Marlin/example_configurations/K8400/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/M150/Configuration_adv.h b/Marlin/example_configurations/M150/Configuration_adv.h
index c2c1c0c3fb..a8379526fd 100644
--- a/Marlin/example_configurations/M150/Configuration_adv.h
+++ b/Marlin/example_configurations/M150/Configuration_adv.h
@@ -807,6 +807,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/RigidBot/Configuration_adv.h b/Marlin/example_configurations/RigidBot/Configuration_adv.h
index 027e633189..2bfdef25f0 100644
--- a/Marlin/example_configurations/RigidBot/Configuration_adv.h
+++ b/Marlin/example_configurations/RigidBot/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/SCARA/Configuration_adv.h b/Marlin/example_configurations/SCARA/Configuration_adv.h
index 9ea1a60bd7..14fb68220f 100644
--- a/Marlin/example_configurations/SCARA/Configuration_adv.h
+++ b/Marlin/example_configurations/SCARA/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/TAZ4/Configuration_adv.h b/Marlin/example_configurations/TAZ4/Configuration_adv.h
index 23b616ad53..c11677a8bd 100644
--- a/Marlin/example_configurations/TAZ4/Configuration_adv.h
+++ b/Marlin/example_configurations/TAZ4/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/TinyBoy2/Configuration_adv.h b/Marlin/example_configurations/TinyBoy2/Configuration_adv.h
index ba0eae98a7..20c2e79f85 100644
--- a/Marlin/example_configurations/TinyBoy2/Configuration_adv.h
+++ b/Marlin/example_configurations/TinyBoy2/Configuration_adv.h
@@ -803,6 +803,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/WITBOX/Configuration_adv.h b/Marlin/example_configurations/WITBOX/Configuration_adv.h
index 3e7f6416d1..e2ed21f47d 100644
--- a/Marlin/example_configurations/WITBOX/Configuration_adv.h
+++ b/Marlin/example_configurations/WITBOX/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h b/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h
index 1ca156d9b3..a8a30eabd4 100644
--- a/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h
@@ -805,6 +805,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h b/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h
index dc5c04e2e0..3e27eab9d9 100644
--- a/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h
@@ -804,6 +804,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/delta/generic/Configuration_adv.h b/Marlin/example_configurations/delta/generic/Configuration_adv.h
index 49a550faee..f7d78f310e 100644
--- a/Marlin/example_configurations/delta/generic/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/generic/Configuration_adv.h
@@ -802,6 +802,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
index 49a550faee..f7d78f310e 100644
--- a/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
@@ -802,6 +802,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
index 3922a31a7a..7f52481171 100644
--- a/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
@@ -807,6 +807,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
index 9b403edb19..41ceff3826 100644
--- a/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
@@ -802,6 +802,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/gCreate_gMax1.5+/Configuration_adv.h b/Marlin/example_configurations/gCreate_gMax1.5+/Configuration_adv.h
index ba963dd06d..4354d717ac 100644
--- a/Marlin/example_configurations/gCreate_gMax1.5+/Configuration_adv.h
+++ b/Marlin/example_configurations/gCreate_gMax1.5+/Configuration_adv.h
@@ -809,6 +809,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   #define PARK_HEAD_ON_PAUSE                  // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/makibox/Configuration_adv.h b/Marlin/example_configurations/makibox/Configuration_adv.h
index c16680356a..f6517a6c15 100644
--- a/Marlin/example_configurations/makibox/Configuration_adv.h
+++ b/Marlin/example_configurations/makibox/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h b/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
index e218c85ca8..a6ab735e58 100644
--- a/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
+++ b/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
@@ -800,6 +800,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc
diff --git a/Marlin/example_configurations/wt150/Configuration_adv.h b/Marlin/example_configurations/wt150/Configuration_adv.h
index 09f94b2260..171f4c3b77 100644
--- a/Marlin/example_configurations/wt150/Configuration_adv.h
+++ b/Marlin/example_configurations/wt150/Configuration_adv.h
@@ -803,6 +803,7 @@
   #define PAUSE_PARK_NO_STEPPER_TIMEOUT       // Enable to have stepper motors hold position during filament change
                                               // even if it takes longer than DEFAULT_STEPPER_DEACTIVE_TIME.
   //#define PARK_HEAD_ON_PAUSE                // Go to filament change position on pause, return to print position on resume
+  //#define HOME_BEFORE_FILAMENT_CHANGE       // Ensure homing has been completed prior to parking for filament change
 #endif
 
 // @section tmc