diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index 864f759982..74dd77c55c 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -783,11 +783,14 @@ static_assert(Y_MAX_LENGTH >= Y_BED_SIZE, "Movement bounds (Y_MIN_POS, Y_MAX_POS
 #endif
 
 #if !defined(TARGET_LPC1768) && ANY( \
-    ENDSTOPPULLDOWNS, \
-    ENDSTOPPULLDOWN_XMAX, ENDSTOPPULLDOWN_YMAX, \
-    ENDSTOPPULLDOWN_ZMAX, ENDSTOPPULLDOWN_XMIN, \
-    ENDSTOPPULLDOWN_YMIN, ENDSTOPPULLDOWN_ZMIN \
-  )
+      ENDSTOPPULLDOWNS, ENDSTOPPULLDOWN_ZMIN_PROBE, \
+      ENDSTOPPULLDOWN_XMAX, ENDSTOPPULLDOWN_YMAX, ENDSTOPPULLDOWN_ZMAX, \
+      ENDSTOPPULLDOWN_XMIN, ENDSTOPPULLDOWN_YMIN, ENDSTOPPULLDOWN_ZMIN, \
+      FIL_RUNOUT_PULLDOWN,  \
+      FIL_RUNOUT1_PULLDOWN, FIL_RUNOUT2_PULLDOWN, FIL_RUNOUT3_PULLDOWN, FIL_RUNOUT4_PULLDOWN, \
+      FIL_RUNOUT5_PULLDOWN, FIL_RUNOUT6_PULLDOWN, FIL_RUNOUT7_PULLDOWN, FIL_RUNOUT8_PULLDOWN, \
+      POWER_LOSS_PULLDOWN, CALIBRATION_PIN_PULLDOWN \
+    )
   #error "PULLDOWN pin mode is not available on the selected board."
 #endif
 
@@ -1146,6 +1149,9 @@ static_assert(Y_MAX_LENGTH >= Y_BED_SIZE, "Movement bounds (Y_MIN_POS, Y_MAX_POS
 #elif ENABLED(SINGLENOZZLE)
 
   #error "SINGLENOZZLE requires 2 or more EXTRUDERS."
+  #if ENABLED(PID_PARAMS_PER_HOTEND)
+    #error "PID_PARAMS_PER_HOTEND must be disabled when using any SINGLENOZZLE extruder."
+  #endif
 
 #endif