diff --git a/Marlin/src/inc/Conditionals_post.h b/Marlin/src/inc/Conditionals_post.h
index e9e282c262..94750d810a 100644
--- a/Marlin/src/inc/Conditionals_post.h
+++ b/Marlin/src/inc/Conditionals_post.h
@@ -1634,7 +1634,7 @@
     #define HAS_E0_MS_PINS 1
   #endif
 
-  #if E_STEPPERS > 1
+  #if E_STEPPERS > 1 || ENABLED(E_DUAL_STEPPER_DRIVERS)
     #if PIN_EXISTS(E1_ENABLE) || AXIS_IS_L64XX(E1) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E1))
       #define HAS_E1_ENABLE 1
     #endif
diff --git a/Marlin/src/module/stepper.cpp b/Marlin/src/module/stepper.cpp
index 3a1ee39c52..649f0d5d23 100644
--- a/Marlin/src/module/stepper.cpp
+++ b/Marlin/src/module/stepper.cpp
@@ -2744,7 +2744,7 @@ void Stepper::init() {
   #if E_STEPPERS && HAS_E0_STEP
     E_AXIS_INIT(0);
   #endif
-  #if E_STEPPERS > 1 && HAS_E1_STEP
+  #if (E_STEPPERS > 1 || ENABLED(E_DUAL_STEPPER_DRIVERS)) && HAS_E1_STEP
     E_AXIS_INIT(1);
   #endif
   #if E_STEPPERS > 2 && HAS_E2_STEP
diff --git a/Marlin/src/module/stepper/indirection.h b/Marlin/src/module/stepper/indirection.h
index 3e3ebd411f..93b765d7a5 100644
--- a/Marlin/src/module/stepper/indirection.h
+++ b/Marlin/src/module/stepper/indirection.h
@@ -751,14 +751,14 @@ void reset_stepper_drivers();    // Called by settings.load / settings.reset
 #endif
 
 #ifndef ENABLE_STEPPER_E1
-  #if E_STEPPERS > 1 && HAS_E1_ENABLE
+  #if (E_STEPPERS > 1 || ENABLED(E_DUAL_STEPPER_DRIVERS)) && HAS_E1_ENABLE
     #define  ENABLE_STEPPER_E1() E1_ENABLE_WRITE( E_ENABLE_ON)
   #else
     #define  ENABLE_STEPPER_E1() NOOP
   #endif
 #endif
 #ifndef DISABLE_STEPPER_E1
-  #if E_STEPPERS > 1 && HAS_E1_ENABLE
+  #if (E_STEPPERS > 1 || ENABLED(E_DUAL_STEPPER_DRIVERS)) && HAS_E1_ENABLE
     #define DISABLE_STEPPER_E1() E1_ENABLE_WRITE(!E_ENABLE_ON)
   #else
     #define DISABLE_STEPPER_E1() NOOP