diff --git a/Marlin/src/module/stepper.cpp b/Marlin/src/module/stepper.cpp
index 2eb5b57758..4a2707215d 100644
--- a/Marlin/src/module/stepper.cpp
+++ b/Marlin/src/module/stepper.cpp
@@ -747,7 +747,6 @@ void Stepper::isr() {
   // Timer interrupt for E. e_steps is set in the main routine;
 
   void Stepper::advance_isr() {
-    nextAdvanceISR = eISR_Rate;
 
     #if ENABLED(MK2_MULTIPLEXER)
       // Even-numbered steppers are reversed